About us

Aim of the project is the development of bioresorbable magnesium-based implants as a therapeutic approach for unresectable tumors. Therefore, different magnesium alloys will be tested for their degradation behavior and antitumor activity to identify suitable candidates for the application in the living organism (in vivo). This novel concept combines the release of antitumor agents and the creation of a harsh environment.

At Hereon, the focus is on the development of suitable magnesium alloys and their processing into test specimens as well as the determination of the degradation behavior and the effect on cancer cells.

Two doctoral students are working on the project: Philipp Globig and Khausik Narasimhan. Of course, a number of other employees are involved in the project.

Philipp Globig

Philipps work addresses the screening of degradation rates of the differently produced magnesium alloys to identify those materials that ensure a balance between sufficient agent/element release and acceptable durability in the organism. As part of cell biological work, these materials will be tested for their cytotoxic potential and antitumor activity to anticipate their behavior in the living organism.

Khausik Narasimhan

Khausik is a materials scientist involved in material development and specimen production in the project.
Khaushik will produce samples in the form of disks / rods / wires and characterise them by microstructure, material properties and degradation behavior. These samples will then be sent to Russia for the ECAP process (nanostructuring).